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  1. Action. Description: Mechanism of Action: Crotamiton is an acaricide agent that acts on the motor system of mites (e.g. Sarcoptes scabiei) through irreversible cessation of spontaneous movements. Additionally, it has antipruritic effects through inhibition of histamine, serotonin, and PAR-2. Onset: Antipruritic effects: 6-10 hr. Pharmacokinetics:

  2. Indications and Dosage. Adult: As 2% nasal ointment: Apply into each nostril 2-3 times daily for 5-7 days. Child: Same as adult dose. Adult: As 2% cream: Apply to affected area tid for up to 10 days according to individual response; re-evaluate after 3-5 days if no clinical response. Child: ≥1 year Same as adult dose.

  3. Tab 1 tab in the morning, midday & in the evening 1 hr before meals. Granules Adult & elderly Acute episodes of ulcerative colitis 1-2 sachets once daily. Maintenance of ulcerative colitis remission 0.5 g tid (in the morning, midday & evening) corresponding to a total dose of 1.5 g daily. Click to view Salofalk detailed prescribing information.

  4. Adult: As 1.5 mg/mL solution: Instil 1 drop into the conjunctival sac 3-4 times daily. As 0.1% solution or susp: Instil 1-2 drops into the affected eye (s) 4-6 times daily. Severe cases: 1-2 drops hourly, then gradually reduce to 1 drop 2-4 hourly to achieve favourable response. As 0.1% ointment: Apply a ribbon of ointment into the conjunctival ...

  5. Indications and Dosage. Adult: 5 mg once daily. Patients with intermittent allergic rhinitis must be managed according to the evaluation of disease history, treatment may be discontinued after the symptoms are resolved and reinitiated upon reappearance; in case of persistent allergic rhinitis, continuous treatment may be considered during the ...

  6. Max: Not to exceed 4.5 g/dose over 30 min. Adult & childn ≥12 yr CrCl 20-40 mL/min Max: 4.5 g every 8 hr, <20 mL/min Max: 4.5 g every 12 hr. Childn <12 yr CrCl ≤50 mL/min 78.75 mg/kg every 8 hr. Click to view Tazocin EF detailed prescribing information.

  7. Inflammatory eye disorders. Adult: As 1% hydrocortisone acetate ointment: Apply 2-4 times daily. As 1% hydrocortisone acetate drops: Severe inflammation: Instil 1 or 2 drops every 30-60 minutes until satisfactory response occurs. Dosage and treatment duration may vary according to the severity of the condition and patient response.