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2016年6月1日 · The study of metagenomics has been much benefited from low-cost and high-throughput sequencing technologies, yet the tremendous amount of data generated make analysis like de novo assembly to consume too much computational resources. In late 2014 we released MEGAHIT v0.1 (together with a brief note …
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MEGAHIT. MEGAHIT is an ultra-fast and memory-efficient NGS assembler. It is optimized for metagenomes, but also works well on generic single genome assembly (small or mammalian size) and single-cell assembly.
2016年6月1日 · MEGAHIT v1.0 can be tuned to suit different applications including single-cell sequencing, and it currently supports five settings. 5 MEGAHIT v1.0 can also output contigs in FASTG format, 6 which allows users to visualize the contig graph using software like[25].
2021年7月30日 · Megahit组装的算法使用的是基于迭代的kmer的DBG法，其特点是超快和超高效内存使用，所以Megahit的软件运行速度极快，节约了大量的拼接时间。. 组装算法大致可以分为三类：. 1.基于OLC (Overlap-Layout-Consensus)，适用于测序量不大的长片段数据. 2.基于kmer的DBG (de bruijn ...
MegaHit is a NGS de novo assembler for assembling large and complex metagenomics data in a time- and cost-efficient manner. It finished assembling a soil metagenomics dataset with 252 Gbps in 44.1 and 99.6 h on a single computing node with and without a graphics processing unit, respectively. MegaHit assembles the data as a whole, i.e. no pre ...
