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2024年8月26日 · Common simvastatin side effects may include: headache; constipation, nausea, stomach pain; or. cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
2024年5月6日 · liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Common Zocor side effects may include: headache; constipation, nausea, stomach pain; or. cold symptoms such as stuffy nose, sneezing, sore throat.
2023年12月4日 · Simvastatin side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Some side effects may not be reported.
2024年7月2日 · Simvastatin 80 mg dose should only be used in patients who have taken this dose chronically (e.g., for 12 months or more) without evidence of muscle toxicity If a patient on simvastatin 80 mg/day needs to initiate an interacting drug (one that will increase simvastatin concentrations); simvastatin should be switched to an alternative statin with less potential for drug-drug interaction.
2024年3月12日 · Uses of Simvastatin Tablets: It is used to slow the progress of heart disease. It is used to lower bad cholesterol and raise good cholesterol (HDL). It is used to lower triglycerides. It is used to lower the chance of heart attack, stroke, and death in some people. It may be given to you for other reasons.
2024年5月16日 · 1. How it works. Simvastatin works by blocking an enzyme in the liver known as HMG-CoA reductase that is responsible for the conversion of HMG-CoA to mevalonate, an important substance necessary for the synthesis of cholesterol and coenzyme Q10. Simvastatin also boosts the breakdown of lipids.
2024年9月25日 · Simvastatin is a prodrug and is hydrolyzed to its active β-hydroxyacid form, simvastatin acid, after administration. Simvastatin acid and its metabolites are inhibitors of HMG-CoA reductase, the rate-limiting enzyme that converts HMG-CoA to mevalonate, a precursor of cholesterol.
2024年10月10日 · Although simvastatin 80 mg daily was evaluated in randomized controlled studies, this dosage is not recommended by FDA because of increased risk of myopathy. Manufacturers state usual dosage range is 5–40 mg daily. Some manufacturers suggest initial dosage of 10 or 20 mg once daily.
Comparing Lipitor vs Simvastatin. View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Lipitor (atorvastatin) Simvastatin. Prescription only. Lipitor is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain.
Simvastatin Interactions There are 319 drugs known to interact with simvastatin , along with 6 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 58 are major, 250 are moderate, and 11 are minor.
