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  1. en.wikipedia.org › wiki › OxycodoneOxycodone - Wikipedia

    Oxycodone, sold under various brand names such as Roxicodone and OxyContin (which is the extended release form), is a semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive[14] and is a commonly abused drug.[15][16] It is usually taken by mouth, and is available in immediate-release and controlled ...

  2. Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum and related species.[23] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis.[24] The toxin causes the ...

  3. Ludwigsburg Palace is a 452-room complex of 18 buildings in Ludwigsburg, Baden-Württemberg, Germany. It is the largest palatial estate in the country and has been called the " Versailles of Swabia ". Eberhard Louis, Duke of Württemberg, began construction of the palace in 1704. Charles Eugene, the son of his successor, completed it and ...

  4. en.wikipedia.org › wiki › MetforminMetformin - Wikipedia

    Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes,[12][13][14][15] particularly in people who are overweight.[13] It is also used in the treatment of polycystic ovary syndrome.[14] It is sometimes used as an off-label adjunct to lessen the risk of metabolic ...

  5. en.wikipedia.org › wiki › Human_penisHuman penis - Wikipedia

    • Structure
    • Development
    • Physiological Functions
    • Evolved Adaptations
    • Clinical Significance
    • Society and Culture
    • Potential Regeneration
    • See Also

    Three main parts of the human penis include: 1. Root: It is the attached part, consisting of the bulb in the middle and the crura, one crus on either side of the bulb. It lies within the superficial perineal pouch. The crus is attached to the pubic arch. 2. Shaft: The pendulous part of the penis. It has two surfaces: dorsal (posterosuperior in the ...

    When the fetus is exposed to testosterone, the genital tubercle elongates (primordial phallus) and develops into the glans and shaft of the penis and the urogenital folds fuse to become the penile raphe. The urethra is developed from the urogenital sinus.

    Urination

    In males, the expulsion of urine from the body is done through the penis. The urethra drains the bladder through the prostate where it is joined by the ejaculatory duct, and then onward to the penis. At the root of the penis (the proximal end of the corpus spongiosum) lies the external sphincter muscle. This is a small sphincter of striated muscle tissueand is in healthy males, under voluntary control. Relaxing the urethral sphincter allows the urine in the upper urethra to enter the penis pr...

    Voiding position

    The distal section of the urethra allows a human male to direct the stream of urine by holding the penis. This flexibility allows the male to choose the posture in which to urinate. In cultures where more than a minimum of clothing is worn, the penis allows the male to urinate while standing without removing much of the clothing. It is customary for some boys and men to urinate in seated or crouched positions. The preferred position may be influenced by cultural or religious beliefs. Research...

    Sexual stimulation and arousal

    The penis incites sexual arousal when sexually stimulated, such as from mental stimuli (sexual fantasy), partnered activity, or masturbation, which can lead to orgasm. The glans and the frenulum are erogenous zones of the penis. The glans has a lot of nerve endings, which makes it the most sensitive. The most effective way to stimulate the penis is through oral (fellatio), manual stimulation (a handjob or manual masturbation), or during sexual penetration. Frotis mutual penile stimulation bet...

    The human penis has been argued to have several evolutionary adaptations. The purpose of these adaptations is to maximise reproductive success and minimise sperm competition. Sperm competition is where the sperm of two males simultaneously occupy the reproductive tract of a female and they compete to fertilise the egg. If sperm competition results ...

    Disorders

    1. Paraphimosisis an inability to move the foreskin forward over the glans. It can result from fluid trapped in a foreskin left retracted, perhaps following a medical procedure, or accumulation of fluid in the foreskin because of friction during vigorous sexual activity. 2. In Peyronie's disease, anomalous scar tissue grows in the soft tissue of the penis, causing curvature. Severe cases can be improved by surgical correction. 3. A thrombosis can occur during periods of frequent and prolonged...

    Terminology

    In many cultures, referring to the penis is considered taboo or vulgar, and a variety of slang words and euphemisms are used to talk about it. In English, these include member, dick, cock, prick, johnson, dork, peter, pecker, manhood, stick, rod, third/middle leg, dong, willy, schlong, and todger. Many of these are used as insults—though sometimes playfully—meaning an unpleasant or unworthy person. Among these, historically, the most commonly used euphemism for penis in English literature and...

    Alteration

    The penis is sometimes pierced or decorated by other body art. Other than circumcision, genital alterations are almost universally elective and usually for the purpose of aesthetics or increased sensitivity. Piercings of the penis include the Prince Albert, apadravya, ampallang, dydoe, deep shaft and frenum piercings. Foreskin restoration or stretching is a further form of body modification, as well as implants under the shaft of the penis. Another type of alteration to the penis is genital t...

    There are efforts by scientists to partially or fully regenerate the structures of the human penis. Patients who can benefit most from this field are those who have congenital defects, cancer, and injuries that have excised parts of their genitalia. Some organizations which perform research into, or conduct regeneration procedures, include the Wake...

  6. Sino-Japanese words are almost exclusively nouns, of which many are verbal nouns or adjectival nouns, meaning that they can act as verbs or adjectives. Verbal nouns can be used as verbs by appending suru (する, "do") (e.g. benkyō suru (勉強する, do studying; study)), while an adjectival noun uses -na (〜な) instead of -no (〜の) (usual for nouns) when acting attributively.

  7. Neil Alden Armstrong (August 5, 1930 – August 25, 2012) was an American astronaut and aeronautical engineer who in 1969 became the first person to walk on the Moon. He was also a naval aviator, test pilot, and university professor. Armstrong was born and raised in Wapakoneta, Ohio. He entered Purdue University, studying aeronautical ...