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  1. Indications and Dosage. Intravenous. Susceptible Gram-negative infections, Susceptible Gram-positive infections, Susceptible infections. Adult: 200 mg on the 1st day given in 1 or 2 infusions, followed by 100-200 mg daily depending on the severity of the infection. Doses are given via infusion over 1-4 hours (depending on the dose).

  2. Child: ≥6 months As immediate release suspension: 10 mg/kg daily for 3 days or 10 mg/kg on day 1, followed by 5 mg/kg/day on days 2-5. >45 kg: Same as adult dose. Adult: 1 g or 2 g as a single dose, in combination with ceftriaxone. Child: >2 years As immediate release preparation: 12 mg/kg/day for 5 days.

  3. Dosage/Direction for Use. FC tab Adult & childn >12 yr 1 g bd. Mild to moderate infections 375 mg tds. More severe infections, resp tract infections 625 mg tds. Oral susp Childn 7-12 yr 312.5 mg tds, 2-7 yr 156.25 mg tds, 9 mth to 2 yr 78.12 mg tds. 457 mg/5 mL oral susp Childn 2 mth-12 yr Mild to moderate infections 25/3.6 mg/kg/day.

  4. Dosage/Direction for Use. IV infusion for up to 14 days (infuse over a 30-min period) or IM inj for up to 7 days. Adult & ped patient ≥13 yr 1 g once daily. Ped patient 3 mth-12 yr 15 mg/kg bd, max 1 g/day. Duration of treatment: Complicated intra-abdominal infections 5-14 days. Complicated skin & skin structure infections, including diabetic ...

  5. Dosage/Direction for Use. 1 tab at the same time daily. Woman who has not used a hormonal contraceptive during the previous mth Start Qlaira on the 1st day of the period. Changing from another combined hormonal contraceptive pill Start the day after taking the last active tab of the previous pill. Changing from combined contraceptive vag ring ...

  6. Drug Interactions. Increased metabolism w/ substances known to induce drug-metabolising enzymes (specifically CYP450 enzymes) eg, anticonvulsants (eg, phenobarb, phenytoin, carbamazepine) & anti-infectives (eg, rifampicin, rifabutin, nevirapine, efavirenz); ritonavir, telaprevir & nelfinavir; herbal prep containing St. John's Wort.

  7. Dosage/Direction for Use. Adult 2 tab daily, morning & noon. In severe cases, morning dose may be increased to 2 tab. Max: 4 tab daily. Elderly >65 yr 1 tab in the morning. In severe cases, 1 tab in the morning, 1 tab at noon. Maintenance: 1 tab in the morning. Click to view Deanxit detailed prescribing information.

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