搜尋結果
Almitrine (marketed as Duxil by Servier) is a diphenylmethylpiperazine derivative classified as a respiratory stimulant by the ATC. It enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies.
2011年9月26日 · Duxaril Tablets, also known as Compound Almitrine Tablets, containing almitrine bismesylate 30mg and raubasine 10mg, is used for treatment of the symptoms of cognitive and chronic sensorineural impairment in elderly (excluding Alzheimer’s
- Identification
- Pharmacology
- Interactions
- Chemical Identifiers
- Properties
Generic Name
1. Almitrine
DrugBank Accession Number
1. DB01430
Background
1. Almitrine is a respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. It is used in the treatment of chronic obstructive pulmonary disease. It is also reported to have a potentially beneficial effect in treating the noctural oxygen desaturation without impairing the quality of sleep.
Indication
1. For the treatment of chronic obstructive pulmonary disease.Reduce drug development failure ratesBuild, train, & validate machine-learning models with evidence-based and structured datasets.See howsee_moreBuild, train, & validate predictive machine-learning models with structured datasets.See how
Associated Conditions
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Contraindications & Blackbox Warnings
1. Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Learn moresee_moreAvoid life-threatening adverse drug events with our Clinical APILearn more
Drug Interactions information
1. This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist. Not Available
Food Interactions
1. Not Available
UNII
1. 9A1222NBG4
CAS number
1. 27469-53-0
InChI Key
1. OBDOVFRMEYHSQB-UHFFFAOYSA-N
Piperazines. Secologanin Tryptamine Alkaloids. Yohimbine. raubasine. almitrine, raubasine drug combination. Almitrine. Cerebral ischemia: from pharmacology to modern techniques and clinical implications. Value of almitrine-raubasin (Duxil Duxaril). International symposium, Hangzhou, People's Republic of China, May 14, 1994.
顯微鏡下的腦細胞 患者的腦部組織與正 常的腦部相比，神經 細胞及神經突觸數目 遽減。 斑塊斑塊(Plaques)， 是產 生於神經元之間的不 正常蛋白質。 神經纖維纏結 (t l ) 是由 串 阿氏痴呆症的細胞 (tangles)，是由一串 串不規則的蛋白質在 細胞內組合而成。
度伐利尤單抗 （ Durvalumab [4] ，商品名 Imfinzi ，中文商品名 英飛凡 ）是一種用於治療癌症的完全人源化 抗PD-L1單株抗體 。 該藥由 阿斯利康 全資子公司MedImmune研發。 [5] 它是一種人類免疫球蛋白G1κ（IgG1κ）單株抗體，可阻斷 PD-L1 與 PD-1 （CD279）。 [6] 臨床應用 [ 編輯] FDA 已批准度伐利尤單抗用於某些類型的膀胱癌和肺癌： [2] 用於鉑類化療失敗後的晚期或轉移性 膀胱癌 的治療。 用於鉑類化療聯合放療失敗的III期非小細胞肺癌的治療。 與 依託泊苷 和 卡鉑 或 順鉑 聯合使用，用於晚期 小細胞肺癌 的一線治療。 NMPA 於2019年12月批准該藥用於鉑類化療聯合放療失敗的III期非小細胞肺癌的治療。
國家食品藥品監督管理局撤銷“都可書"(Duxaril)的註冊 謹請閣下垂注國家食品藥品監督管理局發出通知，決定停止“都可喜"(通用名為阿米三 噱蘿巴新片，叉名複方阿米三嗓片)在國內的生產、銷售和使用，撤銷其批准證明檔。
