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special reports. In an interview with MIMS Doctor, Dr Ka-Yuen Lock, Specialist in Endocrinology, Diabetes and Metabolism in Hong Kong, discussed management of diabetes mellitus (DM), including use of ultra-long-acting insulin, in optimizing glycaemic control. She also shared a case study illustrating improvements in glucose variability and ...
Contents : Per 10/10 mg FC tab Rosuvastatin 10 mg, ezetimibe 10 mg. Per 20/10 mg FC tab Rosuvastatin 20 mg, ezetimibe 10 mg. Indications/Uses : Adjunct to diet for primary hypercholesterolemia as substitution therapy in adult patients adequately controlled w/ individual substances given concurrently at same dose level as in fixed-dose ...
Meniere's disease. Adult: For the treatment of vertigo, tinnitus, hearing loss, and nausea associated with Meniere's disease: As betahistine dihydrochloride: Initially, 8-16 mg tid. Maintenance: 24-48 mg daily in divided doses. As betahistine mesilate: 6-12 mg tid. Adjust doses according to patient needs.
Bioavailability: 17%; increased with a high-fat meal. Time to peak plasma concentration: 30-60 minutes. Distribution: Volume of distribution: 5 L/kg. Metabolism: Metabolised in the liver mainly by the CYP2D6 and to a lesser extent CYP2C19, CYP2B6, and CYP1A2 isoenzymes to 11 metabolites. Excretion: Via urine (98%, as unchanged drug and ...
Gastro-oesophageal reflux disease. Child: 1-16 years Recommended dose: Initially, 0.25 mg/kg 12 hourly via inj over at least 2 minutes or via infusion over 15 minutes, may increase up to 40 mg daily. Oral. Duodenal ulcer. Adult: Recommended dose: 40 mg once daily at bedtime for 4-8 weeks. Alternatively, 20 mg bid.
Indications and Dosage. Adult: For the treatment of bronchopulmonary diseases or conditions associated with excessive mucous secretion: 8 mg tid as needed, may be increased to 16 mg tid for the 1st 7 days. Child: 2-5 years 2 mg tid or 4 mg bid (Max: 8 mg daily); 6-11 years 4-8 mg tid (Max: 24 mg daily); ≥12 years Same as adult dose.
Maintenance: 150 mg daily at bedtime. Child: 3-11 years 4-8 mg/kg daily in 2 divided doses for 4 weeks or up to 8 weeks if needed. Max: 300 mg daily; ≥12 years Same as adult dose. Adult: Symptomatic relief: 150 mg bid for 2 weeks; may be continued for a further 2 weeks in patients with inadequate response.
