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  1. Initially, 1-2 (500-mg tab) or 1 (850-mg tab) daily. Dose may be increased at intervals of several days up to 2 wk. Max dose: 3 g/day. Administration

  2. Apply a thin film of cream to hyperpigmented areas of melasma including about ½ inch of normal appearing skin surrounding each lesion. Rub lightly & uniformly into the skin. Apply once daily at night 30 min before bedtime. Special Precautions. Discontinue if hypersensitivity reaction or HPA axis suppression occur.

  3. Contents. Per tab Dihydrocodeine bitartrate 5 mg, guaifenesin 50 mg, DL-methylephedrine HCl 17.5 mg, chlorpheniramine maleate 1.5 mg. Per 100 mL syrup Dihydrocodeine bitartrate 50 mg, DL-methylephedrine HCl 131.25 mg, guaifenesin 375 mg, chlorpheniramine maleate 15 mg.

  4. Nasal spray 0.1% 1 spray in each nostril. Do not use for >7 consecutive days. Do not exceed 3 applications daily into each nostril. Last application of the day should preferably be shortly before going to bed. Click to view Otrivin detailed prescribing information. Overdosage.

  5. IV Adult & adolescent 12-18 yr 13-31 mL/kg daily infused over 14-24 hr. Max infusion rate: 1.5 mL/kg/hr. Max daily dose: 31 mL/kg. Childn 2-11 yr Up to 31 mL/kg daily infused over 12-24 hr & regularly adjusted to the requirements of the paed patient. Max infusion rate: 1.8 mL/kg/hr. Do not use an infusion period >17 hr at max infusion rate ...

  6. Established hypersensitivity to acetylsalicylic acid or other NSAIDs. History of hepatotoxic reactions to nimesulide. Concomitant exposure to other potentially hepatotoxic substances. Alcoholism, drug addiction. GI ulcer or hemorrhage, bleeding disorders. Severe ...

  7. Mechanism of Action: Xylometazoline is a direct-acting sympathomimetic agent that produces vasoconstriction in the nasal mucosa thereby decreasing nasal blood flow and congestion. Onset: Within 5-10 minutes. Duration: 10 hours.

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