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  1. Data Analysis Tutorials. Review step-by-step guidance on using NHANES data. Low Resolution Video. Low Resolution Video. Last Reviewed: May 30, 2024. Source: National Center for Health Statistics.

  2. EID is a monthly peer reviewed journal covering infectious diseases with emphasis on disease prevention, control, and elimination. Learn More. PCD is a peer reviewed journal covering research, public health findings, innovations, and practices on chronic diseases. Learn More.

    • Background
    • Use in Clinical Decision Making
    • Influenza Testing of Hospitalized Patients
    • Use in Detecting Institutional Influenza Outbreaks
    • Use in Detecting Novel Influenza A Cases
    • Factors Influencing Results of Molecular Assays
    • Interpretation of Testing Results
    • Advantages/Disadvantages of Molecular Assays
    • References

    Molecular assays available for detecting influenza virus infection include rapid molecular assays, Reverse Transcription-Polymerase Chain Reaction (RT-PCR), and other nucleic acid amplification tests. These tests can detect influenza viral RNA or nucleic acids in respiratory specimens with high sensitivity and high specificity. Notably, the detecti...

    Influenza testing is not needed for all outpatients with signs and symptoms of influenza to make antiviral treatment decisions (See See Figure 1, Figure 2). Once influenza activity has been identif...
    Molecular testing is recommended for all hospitalized patients with suspected influenza.
    If treatment is clinically indicated, antiviral treatment should NOT be withheld from outpatients or hospitalized patients with suspected influenza while awaiting influenza testing results.  More i...
    Hospitalized patients with suspected influenza without lower respiratory tract disease should have upper respiratory tract specimens collected for influenza testing by a molecular assay. The Infect...
    More information about antiviral treatment of influenza is available at Antiviral Drugs, Information for Health Care Professionals.
    Collection of lower respiratory tract specimens from hospitalized patients with suspected influenza and pneumonia can be considered for influenza testing by RT-PCR and other molecular assays if inf...
    Molecular assays such as RT-PCR are particularly useful to identify influenza virus infection as a cause of respiratory outbreaks in institutions (e.g., nursing homes, chronic care facilities, and...
    Positive results from one or more ill persons with suspected influenza can support decisions to promptly implement prevention and control measures for influenza outbreaks. Clinicians should be awar...
    Recommendations for control of institutional influenza outbreaks by the Infectious Diseases Society of Americaexternal iconis available.
    Molecular assays, such as RT-PCR, are designed to accurately identify influenza A and B viral RNA or nucleic acids by using conserved gene targets. Some assays will detect influenza A or B viruses...
    Some FDA-cleared devices can detect influenza A or B viruses, and also can identify influenza A hemagglutinin genes, allowing for determination of some or all of the seasonal influenza A virus subt...
    Clinicians and laboratorians using molecular assays that are capable of detecting all currently circulating seasonal influenza A virus subtypes, for example A(H1N1)pdm09, or A(H3N2). and who identi...
    Clinicians and laboratorians using molecular assays that detect influenza A viruses that do not specifically identify currently circulating seasonal influenza A virus subtypes, for example A(H1N1)p...

    Many factors can influence influenza testing results. Influenza viral shedding in the upper respiratory tract generally declines substantially after 4 days in immunocompetent patients with uncomplicated influenza, although infants and young children may have detectable influenza viruses for longer periods. Patients with lower respiratory tract dise...

    Sensitivities and specificities of RT-PCR and other molecular assays that have been cleared by the FDA for diagnostic use are very high compared to other FDA-cleared assays that use different methods. However, even with RT-PCR, false negative results can occur due to improper or poor clinical specimen collection or from poor handling of a specimen ...

    Advantages: 1. Rapid molecular assays and some commercially available molecular assays can produce results in a reasonable time period to inform clinical management (ranging from approximately 15-30 minutes to less than 1.5 hours). 2. Molecular assays are more sensitive and specific for detecting influenza viruses than other influenza tests (e.g., ...

    Ali T, Scott N, Kallas W, et al. Detection of influenza antigen with rapid antibody-based tests after intranasal influenza vaccination (FluMist). Clin Infect Dis. 2004 Mar 1;38(5):760-2. Bell J, Bonner A, Cohen DM, et al. . Multicenter clinical evaluation of the novel Alere™ i Influenza A&B isothermal nucleic acid amplification test. J Clin Virol. ...

  3. 2024年5月7日 · HICPAC is a federal advisory committee appointed to provide advice and guidance to DHHS and CDC regarding the practice of infection control and strategies for surveillance, prevention, and control of healthcare-associated infections, antimicrobial resistance and related events in United States healthcare settings.

  4. The rhabditid nematode (roundworm) Strongyloides stercoralis is the major causative agent of strongyloidiasis in humans. Rarer human-infecting species of Strongyloides are the zoonotic S. fuelleborni ( fülleborni) subsp. fuelleborni and S. fuelleborni subsp. kellyi, for which the only currently known host is humans.

  5. 2024年5月15日 · Health problems caused by secondhand smoke in adults who do not smoke include coronary heart disease, stroke, and lung cancer, as well as adverse reproductive health effects in women, including low birth weight. 1 3.

  6. The National Health Interview Survey (NHIS) has monitored the health of the nation since 1957. NHIS data on a broad range of health topics are collected through personal household interviews. Survey results have been instrumental in providing data to track health status, health care access, and progress toward achieving national health objectives.