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  1. Adult: To reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and postmenopausal women with high risk of invasive breast cancer: 60 mg once daily for 5 years. Recommended therapeutic indications may vary between countries (refer to specific product guidelines).

  2. Metered-dose inhaler releasing fluticasone 250 mcg and formoterol 10 mcg per actuation. Initially, 2 puffs bid, titrated to the lowest effective dose and may be increased by switching to next highest strength combination, depending on patient’s response. Child: Available preparations:

  3. Indications/Uses. Adjuvant treatment after complete tumour resection in adults w/ stage IB-IIIA NSCLC whose tumours have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations. 1st-line treatment of adults w/ locally advanced or metastatic NSCLC w/ activating EGFR mutations.

  4. Undergoes first-pass metabolism in the liver and/or GI tract (oral). Excretion: Via faeces (60% mainly as metabolites) and urine (<10-12% as free and conjugated metabolites). Elimination half-life: 0.5 hr.

  5. Undergoes extensive first-pass metabolism in the gastrointestinal mucosa and liver. Excretion: Mainly via the bile; urine (<2% as unchanged drug). Elimination half-life: Approx 14 hours (atorvastatin); approx 20-30 hours (equipotent metabolites).

  6. Generic Medicine Info. Indications and Dosage. Oral. Cough. Adult: 60 mg up to tid at intervals of at least 6 hours. Dosage recommendations may vary among countries or individual products (refer to specific product guidelines). Child: 2-12 years 1 mg/kg/dose up to tid at intervals of at least 6 hours.

  7. Patient Medicine Information. Why do I need this medicine? Lactulose helps relieve constipation and maintain the regularity of bowel movement. This medicine belongs to a group of medicines called osmotic laxatives. These laxatives work by increasing water into the bowel, which makes the stools softer so it can move out of the body more easily.

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