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2024年3月1日 · The new guidance brings a unified approach to addressing risks from a range of common respiratory viral illnesses, such as COVID-19, flu, and RSV, which can cause significant health impacts and strain on hospitals and health care workers.
- What is an adjuvant and why is it added to a vaccine?
- Adjuvants have been used safely in vaccines for decades.
- Several different adjuvants are used in U.S. vaccines.
- CDC and FDA closely monitor the safety of all vaccines.
An adjuvant is an ingredient used in some vaccines that helps create a stronger immune response in people receiving the vaccine. In other words, adjuvants help vaccines work better. Some vaccines that are made from weakened or killed germs contain naturally occurring adjuvants and help the body produce a strong protective immune response. However, ...
Aluminum salts, such as aluminum hydroxide, aluminum phosphate, and aluminum potassium sulfate have been used safely in vaccines for more than 70 years. Aluminum salts were initially used in the 1930s, 1940s, and 1950s with diphtheria and tetanus vaccines after it was found they strengthened the body’s immune response to these vaccines.
Newer adjuvants have been developed to target specific components of the body’s immune response, so that protection against disease is stronger and lasts longer.
Vaccination providers should review FDA-approved prescribing information or for the most complete and updated information about vaccine components. Package inserts for U.S.-licensed vaccines are available at Vaccines Licensed for Use in the United States | FDA
Information about COVID-19 vaccines authorized for emergency use is available here:COVID-19 Vaccines | FDA
Aluminum
Aluminum-containing adjuvants are vaccine ingredients that have been used in vaccines since the 1930s. Small amounts of aluminum are added to some vaccines to help the body build stronger immunity against the germ in the vaccine. Aluminum is one of the most common metals found in nature and is present in air, food, and water. Previous scientific research has shown the amount of aluminum exposure in people who follow the recommended vaccine schedule is low and is not readily absorbed by the body. Read the research on aluminum exposure and vaccines. Also, see FDA’s web page on common ingredients in U.S. licensed vaccines for more information.
An observational study [PDF – 10 Pages] published in September 2022 identified a possible association between exposure to aluminum from vaccines and later development of persistent asthma in a cohort of children who received care at healthcare organizations participating in the Vaccine Safety Datalink. CDC is not changing vaccine recommendations based on this single study, but further investigation is needed into this potential safety signal.
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CDC and the Food and Drug Administration (FDA) are committed to ensuring that vaccines provided to the public are safe and effective. Once vaccines are licensed or authorized for emergency use in the United States, CDC and FDA continuously monitor them through several safety systems. Learn more about CDC’s vaccine safety systems.
New guidance on COVID-19 vaccination and pemivibart (Pemgarda™), a monoclonal antibody authorized for COVID-19 pre-exposure prophylaxis in people who are moderately or severely immunocompromised and meet the FDA-authorized conditions for use.
Ingredients in specific vaccines. The Food and Drug Administration (FDA), which is responsible for making sure vaccines are safe and effective, has information about all approved vaccines. Check out the below links to discover the different vaccine options and the various ingredients. FDA-approved vaccines.
COVID-19 (coronavirus disease 2019) is a disease caused by a virus named SARS-CoV-2. It can be very contagious and spreads quickly. View All. For Everyone. View all. Find links to guidance and information on all topics related to COVID-19, including the COVID-19 vaccine.
The CDC recommends pneumococcal vaccination for all infants and children younger than 2 years of age and all adults 65 years or older. In certain situations, other children and adults should also be vaccinated.
Listeriosis is a serious infection usually caused by eating food contaminated with the bacterium Listeria monocytogenes. An estimated 1,600 people get listeriosis each year, and about 260 die. The infection is most likely to sicken pregnant women and their newborns, adults aged 65 or older, and people with weakened immune systems.
