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  1. bestpractice.bmj.com › topics › en-gbPneumocystis jirovecii pneumonia - BMJ Best Practice

    2024年2月2日 · Suspicion for Pneumocystis pneumonia (PCP) is based on clinical signs or symptoms of pneumonia in a person with immune suppression, especially when due to HIV infection. Diagnosis is made by detection of the organism in either induced sputum or bronchoalveolar lavage.

    • Summary

      PCP is an infection of the lung caused by the fungal ...

  2. radiopaedia.org › articles › pulmonary-pneumocystis-jiroveciiPulmonary Pneumocystis jirovecii infection - Radiopaedia.org

    • Terminology
    • Epidemiology
    • Clinical Presentation
    • Pathology
    • Radiographic Features
    • Treatment and Prognosis
    • Differential Diagnosis
    • See Also

    Classically, "PCP" was the acronym for Pneumocystis carinii pneumonia, but the causative organism was reclassified as Pneumocystis jirovecii. Pneumocystis carinii refers to a species found in rats, while Pneumocystis jirovecii refers to the human isolate 14. However, there continues to be widespread use of the acronym PCP; a post hoc justification ...

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    Pneumocystis pneumonia is virtually never present in immunocompetent individuals. It is one of the most common causes of life-threatening pulmonary infections in HIV-positive patients. It occurs twice as frequently in homosexual males versus intravenous drug users (IVDU). It typically occurs at CD4 counts <200 cells/mm 3,8. It is seen particularly ...

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    Presentation is usually non-specific and insidious, the most common symptoms being dyspnea and/or non-productive cough. In patients who are profoundly immunocompromised, onset may be more dramatic and resemble other pulmonary infections 7,9. The diagnosis can often be confirmed with bronchoalveolar lavage which has a sensitivity of 85-90% 8. It is ...

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    Pneumocystis jirovecii is an atypical yeast-like fungus of the genus Pneumocystis 10that was previously thought to be a protozoan. Histology of infected lung demonstrates intra-alveolar eosinophilic masses with a foamy appearance, due to small cysts within which the Pneumocystis jirovecii organism is found 9. Culturing Pneumocystis jirovecii can be...

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    Although up to 90% of chest radiographs in patients with Pneumocystis pneumonia are abnormal, appearances are often non-specific. Between 10-15% of patients have normal chest radiographs and close to 30% have non-specific or inconclusive findings 2-4,6,7. Features which are highly suggestive of pneumocystis pneumonia in patients with CD4 counts bel...

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    Most patients with acute infection are treated with trimethoprim-sulfamethoxazole (co-trimoxazole or TMP-SMZ) 17, combined with corticosteroids in patients with moderate to severe infections 8. The same agent may be used as prophylaxis. A number of alternative agents may also be employed, both for acute treatment and prophylaxis, although these are...

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    The differential diagnosis on HRCT is strongly influenced by knowledge of HIV status and CD4 count. In these patients the differential includes: 1. viral pneumonitis: similar, but cysts are absent 1.1. CMV pneumonitis 1.2. COVID-19 2. mycobacterium tuberculosis: when upper zone cysts are prominent and if tree-in-bud opacities are present 3. angioin...

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    pulmonary manifestations of HIV/AIDS
    pulmonary fungal infection

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  4. www.ncbi.nlm.nih.gov › books › NBK482370Pneumocystis jirovecii Pneumonia - StatPearls - NCBI Bookshelf

    2023年1月21日 · Pneumocystis carinii pneumonia (PCP), now referred to as Pneumocystis jirovecii pneumonia, is a fungal infection that most commonly affects the immunocompromised and, in some cases, can be severely life-threatening (see Image.

    • Justina Truong, John V. Ashurst
    • Kingman Regional Medical Center
    • 2021
    • 2023/01/21

  5. www.hopkinsmedicine.org › pneumocystis-pneumonia-or-pcpPneumocystis Pneumonia or PCP | Johns Hopkins Medicine

    Pneumocystis pneumonia or PCP is a fungal infection in one or both lungs. It is common in people who have a weak immune system, such as people who have AIDS. The disease is less common in the U.S. than it used to be. When it happens, you need medical attention right away. What causes PCP? The fungus Pneumocystis jiroveci causes PCP.

  6. en.wikipedia.org › wiki › Pneumocystis_pneumoniaPneumocystis pneumonia - Wikipedia

    Pneumocystis pneumonia (PCP), also known as Pneumocystis jirovecii pneumonia (PJP), is a form of pneumonia that is caused by the yeast-like fungus Pneumocystis jirovecii. [3][4] Pneumocystis specimens are commonly found in the lungs of healthy people although it is usually not a cause for disease. [5]

  7. www.cdc.gov › pneumocystis-pneumoniaPneumocystis Pneumonia Basics - CDC

    2024年4月24日 · Pneumocystis pneumonia (PCP) is a serious lung infection that affects people with weakened immune systems. PCP is airborne, spreading person-to-person, and can cause symptoms, like fever, cough, and chest pain. Treatment for PCP must include PCP can

  8. www.cedars-sinai.org › p › pneumocystis-pneumonia-or-pcpPneumocystis Pneumonia or PCP - Cedars-Sinai

    Your healthcare provider can diagnose PCP based on your health history and a physical exam. You may need these tests: Chest X-ray. This test uses a small amount of radiation to make images of internal tissues, bones

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