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  1. Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are now believed to be variants of the same condition, distinct from erythema multiforme. SJS/TEN is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss. Using current definitions, it is nearly always caused by ...

  2. dermnetnz.org › topics › sjs-ten-imagesSJS-TEN images - DermNet

    SJS-TEN images — extra information Synonyms: SJS images, TEN images, Stevens Johnson syndrome images, Toxic epidermal necrolysis images

  3. SJS/TEN often presents with a few days of prodromal illness with fever (> 39 C), malaise, cough, a blocked or runny nose, sore throat and sore eyes. The rash then appears and extends over 5–7 days. It usually starts on the face, chest, and the proximal limbs, and then spreads widely. The rash is painful and itchy.

  4. Drug hypersensitivity syndrome is sometimes also called drug reaction with eosinophilia and systemic symptoms (DRESS), and drug-induced hypersensitivity syndrome (DIHS). The syndrome is classified as a severe cutaneous adverse reaction (SCAR). It may have overlapping features with Stevens–Johnson syndrome / toxic epidermal necrolysis (SJS/TEN ...

  5. Clinical features. Toxic epidermal necrolysis (T.E.N.) is characterised by fever (>38C), widespread tender erythema affecting >30% skin surface associated with mucosal involvement. Erythema is followed by extensive full thickness cutaneous and mucosal necrosis and denudation within 2 or 3 days. Similar symptoms and signs involving less than 10% ...

  6. The blistering of large areas of skin gives the appearance of a burn or scalding, hence the name staphylococcal scalded skin syndrome. SSSS is often used interchangeably with the eponymous name Ritter von Ritterschein disease (Ritter disease), particularly when it presents in newborn children. Superficial blistering over the axillae, face and ...

  7. 2021年9月1日 · Erythema multiforme is an immune-mediated, typically self-limiting, mucocutaneous condition characterised by ‘target’ lesions. Significant mucosal involvement distinguishes erythema multiforme major from multiforme minor. Episodes can be isolated, recurrent, or persistent. In most cases, erythema multiforme is precipitated by herpes simplex ...

  8. SJS/TEN is characterised by an extensive necrosis and detachment of the epidermis, which involves skin and mucosal surfaces (genitals, eyes, and mouth). The nursing care described on this page is adapted from the Créteil protocol for patients with toxicepidermal necrolysis [1]. Mucosal involvement. Epidermal necrolysis.

  9. A target lesion is a round skin lesion with three concentric colour zones: A bright red outermost ring. Target lesions typically occur in erythema multiforme. They can arise on any body site, including face, upper chest, back, arms, legs, hands, feet and mucous membranes (such as the lips). A target lesion is also called a bulls-eye lesion or a ...

  10. EM is more common in men than women and 50% are under 20 years of age. It is an eruption of classic target lesions on the extremities associated with mild fever and malaise. It persists for one to three weeks. EM minor is mostly preceded by infection. Common causes are: Herpes simplex (often labial) Orf. Other viral infections.

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