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副作用: 輕微或短暫的血管舒張、低血壓，少數會產生短暫的視覺改變、胸痛。 若長期服用可能會有齒齦增殖、乳房不正常賬大，短暫血糖過高、影響肝功能。 以上資料只供參考,不能作診症用途, 請與家庭醫生查詢並作出適合治療. 如身體不適請即睇醫生,切勿延誤治療。 如有錯漏請提出糾正,我們會盡快跟進, 本站恕不會負任何責任. < 上一則 下一則 > 即時提問 ? 藥物資訊. 藥物資料庫NUFEDIPINE-Adalat retard,藥物資訊 ,副作用.
The usual maintenance dose of Adalat Retard (20mg strength) is 1 tablet, every 12 hours (i.e. twice per day), but your doctor may increase or decrease the dose depending on how well your blood
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How much nifedipine can I take Adalat retard?
The usual maintenance dose of Adalat Retard (20 mg strength) is 1 tablet, every 12 hours (i.e. twice per day), but your doctor may increase or decrease the dose depending on how well your blood pressure or angina is being controlled.
- Posology and Method of Administration
- Contraindications
- Interaction with Other Medicinal Products and Other Forms of Interaction
- Fertility, Pregnancy and Lactation
- Effects on Ability to Drive and Use Machines
- Overdose
- Pharmacodynamic Properties
- Pharmacokinetic Properties
- Preclinical Safety Data
Method of administration Oral use. As a rule, tablets are swallowed whole with a little liquid, either with or without food. Adalat retard should not be taken with grapefruit juice (see Section 4.5). Dosage regimen The recommended starting dose of Adalat retard is 10 mg every 12 hours swallowed with water with subsequent titration of dosage accordi...
Adalat retard must not be administered to patients with known hypersensitivity to nifedipine, or to other dihydropyridines because of the theoretical risk of cross-reactivity, or to any of the excipients (see section 4.4 and 6.1). Adalat retard must not be used in cases of cardiogenic shock, clinically significant aortic stenosis, unstable angina, ...
Drugs that affect nifedipine Nifedipine is metabolised via the cytochrome P450 3A4 system, located both in the intestinal mucosa and in the liver. Drugs that are known to either inhibit or to induce this enzyme system may therefore alter the first pass (after oral administration) or the clearance of nifedipine (see Section 4.4). The extent as well ...
Pregnancy Adalat retard should not be used during pregnancy unless the clinical condition of the woman requires treatment with nifedipine (see Section 4.4). In animal studies, nifedipine has been shown to produce embryotoxicity, foetotoxicity and teratogenicity (see Section 5.3). There are no adequate and well-controlled studies in pregnant women. ...
Reactions to the drug, which vary in intensity from individual to individual, may impair the ability to drive or to operate machinery (see Section 4.8). This applies particularly at the start of treatment, on changing the medication and in combination with alcohol. Adverse drug reactions (ADRs) based on placebo-controlled studies with nifedipine so...
Symptoms The following symptoms are observed in cases of severe nifedipine intoxication: Disturbances of consciousness to the point of coma, a drop in blood pressure, tachycardia, bradycardia, hyperglycaemia, metabolic acidosis, hypoxia, cardiogenic shock with pulmonary oedema. Treatment As far as treatment is concerned, elimination of nifedipine a...
ATC code: C08CA05 Nifedipine is a specific and potent calcium antagonist of the 1, 4-dihydropyridine type. Calcium antagonists reduce the transmembranal influx of calcium ions through the slow calcium channel into the cell. Nifedipine acts particularly on the cells of the myocardium and the smooth muscle cells of the coronary arteries and the perip...
Absorption After oral administration nifedipine is rapidly and almost completely absorbed. The systemic availability of orally administered nifedipine is 45 - 56 % owing to a first pass effect. Maximum plasma and serum concentrations are reached at 1.5 to 4.2 hours with Adalat retard (20 mg tablets). Simultaneous food intake leads to delayed, but n...
Preclinical data reveal no special hazard for humans based on conventional studies of single and repeated dose toxicity, genotoxicity and carcinogenic potential. Reproduction toxicology Nifedipine has been shown to produce teratogenic findings in rats, mice and rabbits, including digital anomalies, malformation of the extremities, cleft palates, cl...
In mild to moderate hypertension, the recommended initial dose is one 20 mg tablet once-daily. In severe hypertension, the recommended initial dose is one 30 mg tablet once-daily. If necessary, the dosage can be increased according to individual requirements
2023年9月19日 · The starting dose for patients, not previously prescribed Adalat Retard products is one tablet once daily. The recommended dose in hypertension and angina prophylaxis is 20 mg twice daily during or after food. Dosage may be adjusted within the range 10 mg twice daily to 40 mg twice daily.
Adalat retard is used to treat high blood pressure or angina (chest pain). For high blood pressure: Adalat retard works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart.
