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  1. 辉瑞-BioNTech 2019冠状病毒病疫苗 [5] (英語: Pfizer–BioNTech COVID-19 vaccine ,簡稱: 輝瑞BNT疫苗 、 輝瑞疫苗 、 BNT疫苗 [4] ,代號: BNT162b2 , 商品名 : Comirnaty [2] 、 復必泰 , 國際非專利藥品名稱 :tozinameran [1] ),是一種專門對抗 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV2)的 2019冠状病毒病疫苗 [3] ,為一種 信使核糖核酸 (mRNA)疫苗 [6] ,由德國 BioNTech 及美國 輝瑞 合作開發 [7] [8] 。

    • BNT162b2, 輝瑞-BioNTech COVID-19疫苗, 輝瑞疫苗, BioNTech疫苗, BNT疫苗, 復星醫藥-BioNTech COVID-19疫苗
    • 肌肉注射
    • Comirnaty, 復必泰
  2. Medical uses. The Pfizer–BioNTech COVID-19 vaccine is used to provide protection against COVID-19, caused by infection with the SARS-CoV-2 virus, by eliciting an immune response to the S antigen. [1] [2] [30] [39] The vaccine is used to reduce morbidity and mortality from COVID-19.

    • Comirnaty
    • mRNA
    • Should Pregnant and Breastfeeding Women Be Vaccinated?
    • Who Should Not Take The Vaccine?
    • Is This Vaccine Recommended For Children and Adolescents?
    • How Efficacious Is The Vaccine?
    • What Is The Recommended Dosage?
    • Is A Booster Dose Recommended For This Vaccine?
    • Can This Vaccine Be ‘Mixed and Matched’ with Other Vaccines?
    • Does It Prevent Infection and Transmission?
    • Does It Work Against New Variants?
    • How Does This Vaccine Compare to Other Covid-19 Vaccines in use?

    Given the adverse consequences of COVID-19 disease during pregnancy and the increasing data supporting a favorable safety profile of BNT162b2 in pregnancy, WHO recommends the use of BNT162b2 in pregnant individuals. WHO does not recommend pregnancy testing prior to vaccination. WHO does not recommend delaying pregnancy or terminating pregnancy beca...

    People with a history of severe allergic reaction to any component of the vaccine should not take it. Anyone with fever (body temperature over 38.5 ºC) should postpone vaccination until they are afebrile.

    This vaccine is authorized for use for those aged 6 months and older, with an adjustment in the recommended dosage for those aged 6 months to 4 years, and an adjustment for those aged 5-11 years. WHO recommends that countries should consider using the vaccine in children aged 6 months and older to 17 only when high vaccine coverage with 2 doses has...

    The Pfizer BioNTech vaccine against COVID-19 has very high efficacy against severe disease and moderate efficacy against symptomatic SARS-CoV-2 infection.

    For all persons aged 12 years and above, SAGE recommends two doses (30 µg, 0.3 ml each), 4-8 weeks apart given intramuscularly into the deltoid muscle. For children aged 5 to 11 years SAGE recommends two doses (10 µg, 0.2 ml each) given intramuscularly into the deltoid muscle and provided 4-8 weeks apart, preferentially 8 weeks. For infants and chi...

    The first booster dose is recommended for the highest priority-use groups (e.g. older adults, persons with moderate to severe immunocompromising conditions, and health workers) followed by lower priority-use groups, 4-6 months after the completion of the primary series. If more than 6 months have elapsed since completion of the primary series, the ...

    SAGE accepts two doses from different COVID-19 vaccine platforms of WHO Emergency Use Listing (EUL) COVID-19 vaccines as a complete primary series. For countries considering mix-and match schedules, WHO has made recommendations to ensure equivalent or favourable immunogenicity or vaccine effectiveness for heterologous versus homologous schedules: 1...

    There is modest vaccine impact on transmission. In the meantime, we must maintain and strengthen public health measures that work: masking, physical distancing, handwashing, respiratory and cough hygiene, avoiding crowds, and ensuring good ventilation.

    The vaccine remains effective against virus variants, though for the Omicron variant, vaccine effectiveness against severe and mild disease after two doses is lower compared to Delta, and waning is more rapid. Therefore, a third dose (first booster) is recommended for all adults, and a second booster for the highest priority-use groups.

    It is impossible to compare vaccines head-to-head due to the different approaches taken in designing the respective studies, but overall, all of the vaccines that have achieved WHO Emergency Use Listing are highly effective in preventing severe disease and hospitalization due to COVID-19. This webpage was updated on 18 August 2022 to reflect the la...

  3. 2022年4月1日 · 香港與澳門使用的復必泰(BNT/輝瑞疫苗)是與輝瑞合作研發疫苗BNT162b2的德國BioNTech生物科技公司2020年8月與中國復星醫藥簽約合作生產的同款疫苗。 復星醫藥向中國引進mRNA疫苗的申請尚未獲批准。 上海市政府的支持政策公布後,復星醫藥 (02196)A股飆升逾7.7%,港股收漲8.3%。...

    地點
    完全接種比例
    總劑數
    全球
    61
    12120524547
    中國大陸、香港和澳門
    87
    3403643000
    印度
    66
    1978918170
    美國
    67
    596233489
  4. 2022年8月18日 · 世卫组织免疫战略咨询专家组已发布使用辉瑞-生物科技(BNT162b2)COVID-19疫苗的临时建议。 本文对这些临时建议做了归纳。 你可以在 此处 查阅完整指导文件。 以下是你需要了解的内容。 免疫战略咨询专家组认为,辉瑞-生物科技COVID-19 mRNA疫苗安全有效。 哪些人可以接种该疫苗? 该疫苗对6个月龄及以上的所有个人都安全有效。 根据 世卫组织优先次序路线图 和 世卫组织价值观框架 ,老年人、免疫功能低下者和卫生工作者为最高优先使用群体。 应尽一切努力在最高和高度优先使用群体中实现高疫苗接种覆盖率。 孕妇和哺乳期妇女是否应接种疫苗? 鉴于妊娠期患COVID-19的不良后果以及已有越来越多的数据证实BNT162b2疫苗在妊娠期具有良好的安全性,世卫组织建议妊娠妇女使用此疫苗。

  5. 2020年12月10日 · The results demonstrate that Covid-19 can be prevented by immunization, provide proof of concept that RNA-based vaccines are a promising new approach for protecting humans against infectious ...

  6. 2020年11月18日 · Primary efficacy analysis demonstrates BNT162b2 to be 95% effective against COVID-19 beginning 28 days after the first dose;170 confirmed cases of COVID-19 were evaluated, with 162 observed in the placebo group versus 8 in the vaccine group.

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