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Indications/Uses. Regular treatment of asthma where use of a combination (inhaled corticosteroid & long-acting β 2 -agonist) is appropriate in adults & adolescents who are symptomatic on inhaled corticosteroid therapy; or who are established on regular long-acting β 2 -agonist & inhaled corticosteroid therapy.
Recommended maintenance dose: 2 inhalations daily (as 1 inhalation in the morning & evening or as 2 inhalations in either the morning or evening). 2 inhalations bd may be appropriate for some patients. Total daily dose: Up to 12 inhalations can be used temporarily.
Indications/Uses. Add on therapy in adults w/ essential HTN whose BP is inadequately controlled on amlodipine alone. Replacement therapy in adult patients w/ essential HTN who are receiving telmisartan & amlodipine from separate tablets. Click to view Twynsta detailed prescribing information.
For doses >80 mg daily, divide dose & give bd. For rapid acid control, starting dose of 2 x 80 mg w/in 1 hr. Patient w/ severe liver impairment Max: 20 mg daily. Click to view Pantoloc detailed prescribing information
Add-on treatment for adults w/ relapsing-remitting or refractory eosinophilic granulomatosis w/ polyangiitis (EGPA). Add-on treatment for adults w/ inadequately controlled hypereosinophilic syndrome (HES) w/o an identifiable non-haematologic secondary cause. Click to view Nucala detailed prescribing information. Dosage/Direction for Use.
Essential HTN in adults whose BP is not adequately controlled on valsartan or hydrochlorothiazide monotherapy. Click to view Co-Diovan detailed prescribing information. Dosage/Direction for Use. 1 tab once daily. Click to view Co-Diovan detailed prescribing information. Overdosage.
Increased systemic exposure w/ inhibitors of uptake transporter (rifampicin, ciclosporin) or efflux transporter (ritonavir). Dual blockade of the renin-angiotensin-aldosterone system w/ ACE inhibitors, angiotensin receptor blockers, or aliskiren. Click to view Exforge detailed prescribing information.
