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  1. en.wikipedia.org › wiki › OxycodoneOxycodone - Wikipedia

    Oxycodone, sold under various brand names such as Roxicodone and OxyContin (which is the extended release form), is a semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive[14] and is a commonly abused drug.[15][16] It is usually taken by mouth, and is available in immediate-release and controlled ...

    • By mouth: 60–87%
    • AU: C
    • C₁₈H₂₁NO₄
    • OxyContin, Endone, others
  2. Out of Darkness (previously titled The Origin) is a 2022 British adventure horror thriller film directed by Andrew Cumming in his feature length debut and starring Safia Oakley-Green and Chuku Modu . Out of Darkness had its world premiere at the BFI London Film Festival on 6 October 2022. The film was nominated for five awards at the 2023 ...

  3. en.wikipedia.org › wiki › LupusLupus - Wikipedia

    Lupus, technically known as systemic lupus erythematosus ( SLE ), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [1] Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers ...

  4. en.wikipedia.org › wiki › Dark_matterDark matter - Wikipedia

    History Early history The hypothesis of dark matter has an elaborate history. In the appendices of the book Baltimore lectures on molecular dynamics and the wave theory of light where the main text was based on a series of lectures given in 1884, Lord Kelvin discussed the potential number of stars around the Sun from the observed velocity dispersion of the stars near the Sun, assuming that the ...

    • Background
    • Concept
    • Relationship to Other Proposed Fermi Paradox Solutions
    • Game Theory
    • Science Fiction Versions

    There is no known reliable or reproducible evidence that aliens have visited or attempted to contact Earth. No transmissions and no firm evidence of intelligent extraterrestrial life have been detected or observed. This runs counter to the knowledge that the universe is filled with a very large number of planets, some of which likely hold condition...

    The "dark forest" hypothesis presumes that any space-faring civilization would view any other intelligent life as an inevitable threat and thus destroy any nascent life that makes itself known. As a result, the electromagnetic spectrumwould be relatively quiet, without evidence of any intelligent alien life. A similar hypothesis, under the name "de...

    The Berserker hypothesis, also known as the deadly probes scenario, proposes self-reproducing machines seek to destroy organic life.: 112 The name derives from short stories by Fred Saberhagenwritten in the 1960s.The dark forest hypothesis is distinct from the Berserker hypothesis in that under the former, many alien civilizations could still exist...

    The dark forest hypothesis is a special case of the "sequential and incomplete information game" in game theory. In game theory, a "sequential and incomplete information game" is one in which all players act in sequence, one after the other, and none are aware of all available information. In the case of this particular game, the only win condition...

    In addition to Fred Saberhagen's Berserker novels,: 112 variations of these ideas have been used in other science fiction stories. These include Alistair Reynolds’ Redemption Ark series, Gregory Benford and Larry Niven in Starship, and Greg Bear in The Forge of God. In 1987, science fiction author Greg Bear explored this concept that he called a "v...

  5. Dark is a German science fiction thriller television series co-created by Baran bo Odar and Jantje Friese. It ran for three seasons from 2017 to 2020. The story follows characters from the fictional town of Winden, Germany, as they pursue the truth in the aftermath of a child's disappearance. They follow connections between four estranged families to unravel a sinister time travel conspiracy ...

  6. en.wikipedia.org › wiki › LolitaLolita - Wikipedia

    Lolita is a 1955 novel written by Russian-American novelist Vladimir Nabokov that addresses the controversial subject of hebephilia. The protagonist is a French literature professor who moves to New England and writes under the pseudonym Humbert Humbert. He describes his obsession with a 12-year-old "nymphet", Dolores Haze, whom he kidnaps and ...

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