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  1. 2022年6月13日 · Omicron亞型變異株BA.4及BA.5分別於今年1月及2月首次現蹤於南非。 根據研究顯示,這二株病毒株均有「傳染力較高」及「免疫逃脫」的特性,具有社區傳播的能力。 今年4月至5月期間,這兩株病毒已於南非引發第五波疫情,近期開始在歐美流行,7月6日更突破國門防線,正式入侵台灣,引發國人關注。 BA.4、BA.5的傳染力高嗎?...

    • What Are Ba.4 and Ba.5?
    • Why Are The Variants on The Rise Globally?
    • What Impact Will Ba.4 and Ba.5 Have on Society?
    • How Well Do Vaccines Work Against The Variants?
    • What Will Come Next?

    The two variants are more similar to BA.2 than to the BA.1 strain that kicked off most countries’ Omicron waves late last year. But BA.4 and BA.5 carry their own unique mutations, including changes called L452R and F486V in the viral spike protein that might tweak its ability to latch onto host cells and skirt some immune responses. A May preprint1...

    Variants’ transmission advantages can result from biological changes that speed infection, for instance, allowing the virus to infect more people, more quickly. But the rise of BA.4 and BA.5 seems to stem, instead, from their capacity to infect people who were immune to earlier forms of Omicron and other variants, says Christian Althaus, a computat...

    This, too, is likely to vary by country. Despite high case numbers, South Africa experienced only a small rise in hospitalizations and deaths during its BA.4 and BA.5 wave, says Waasila Jassat, a public-health specialist at the country’s National Institute for Communicable Diseases in Johannesburg. In a study that will soon be posted to the medRxiv...

    Lab studies consistently suggest that antibodies triggered by vaccination are less effective at blocking BA.4 and BA.5 than they are at blocking earlier Omicron strains, including BA.1 and BA.22–6. This could leave even vaccinated and boosted people vulnerable to multiple Omicron infections, scientists say. Even people with hybrid immunity, stemmin...

    That’s anybody’s guess. The parade of Omicron subvariants could continue, with new variants picking further holes in existing immunity. “Nobody can say BA.4/5 is the final variant. It is highly probable that additional Omicron variants will emerge,” says Kei Sato, a virologist at the University of Tokyo. Researchers have identified several spots on...

    • Ewen Callaway
  2. 2022年8月17日 · 新英格蘭醫學雜誌發表研究報告稱BA.4和BA.5可以基本逃脫疫苗接種或曾經感染的免疫保護即它們逃避免疫阻遏的能力很強。 《科學》雜誌上的一項研究還表明,初始的奧密克戎變異株就像一種「隱形病毒」,使人的免疫系統對後來的亞型變異株降低警惕性,辨識力降低。 這是科學家所稱的「免疫印記」作用。...

  3. 2022年9月4日 · Omicron BA.4、BA.5來襲!自新冠疫情爆發以來,全球相繼出現Alpha、Beta、Gamma、Delta和Omicron新冠變異病毒株。到底變種病毒Omicron亞型變種株BA.4、BA.5患者會出現甚麼病徵?與BA.2 有何不同?一文了解症狀、潛伏期、疫苗效用等資訊。

  4. 2022年8月9日 · BA.4 and BA.5 were first detected in South Africa in January and February 2022, respectively. 1 They are offshoots of the omicron variant BA.2, though their additional mutations seem to have given them a transmission advantage. 2. What’s the difference between BA.4 and BA.5?

  5. 2022年6月13日 · 指揮中心13日公布境外攔截5Omicron亞型變異株,分別是4BA.5以及1例BA.4,近期本土個案仍以BA.2為主流病毒株。 BA.4BA.5變異株源自哪? 在境外的盛行情形是如何? 傳染力與特性為何? 《公視新聞網》整理3大問答釋疑。

  6. BA.4 and BA.5 Omicron: How worried should we be? Surges of Covid are happening again around the world, driven by some new subvariants of Omicron.