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2023年1月7日 · Stevens-Johnson syndrome (SJS) is a rare, serious disorder of the skin and mucous membranes. It's usually a reaction to medication that starts with flu-like symptoms, followed by a painful rash that spreads and blisters. Then the top layer of affected skin dies, sheds and begins to heal after several days.
史蒂芬斯－強森综合征 （英語： Stevens-Johnson syndrome ，縮寫SJS），又稱 史提芬強生症候群 、 史帝文生氏－強生症候群 、 史帝文生－強生症候群 ，是多型性紅斑（Erythema multiforme）的一種，能影響表皮的細胞死亡，導致真皮與表皮分離，是一種可致命的 ...
- EB13.0
- 皮肤病学
- 695.13、695.15
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What is Stevens-Johnson syndrome (SJS)?
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What causes Stevens-Johnson syndrome?
Steven-Johnson综合征和中毒性表皮坏死松解症（TEN）是严重的皮肤过敏反应。 药物，尤其是磺胺类药物、抗癫痫药和抗生素是最常见的原因。 斑疹迅速扩展并融合，导致表皮水疱、坏死和松解。 根据原发皮损表现和临床综合征可得到明确诊断。 治疗是支持性护理；环孢素、血浆置换或 IV 免疫球蛋白、早期皮质类固醇治疗和肿瘤坏死因子-α 抑制剂已被使用。 儿童死亡率高达7.5%，成人中高达20%～25%，早期治疗可降低死亡率。 Stevens-Johnson综合征和中毒性表皮坏死松解症的临床表现类似，只是皮损分布有所不同。 依照普遍接受的定义，SJS受累面积 < 体表面积的10%，而TEN则 > 体表面积的30%；10%～30%体表面积受累的认为是SJS/TEN重叠。
- Julia Benedetti
Stevens–Johnson syndrome ( SJS) is a type of severe skin reaction. [1] Together with toxic epidermal necrolysis (TEN) and Stevens–Johnson/toxic epidermal necrolysis (SJS/TEN) overlap, they are considered febrile mucocutaneous drug reactions and probably part of the same spectrum of disease, with SJS being less severe.
- Age < 30
2022年4月29日 · Stevens-Johnson syndrome (SJS) is a rare and extremely serious condition that causes your skin to come loose and detach. It was once known as Lyell’s syndrome, and it’s sometimes...
2023年4月10日 · Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
